Preparation, characterization and antitumor activity evaluation of silibinin nanoparticles for oral delivery through liquid antisolvent precipitation
نویسندگان
چکیده
منابع مشابه
Preparation and characterization of amorphous amphotericin B nanoparticles for oral administration through liquid antisolvent precipitation.
We prepared amphotericin B (AmB) nanoparticles through liquid antisolvent precipitation (LAP) and by freeze-drying to improve the solubility of AmB for oral administration. The LAP was optimized through a single-factor experiment. We determined the effects of surfactants and their concentration, the stirring time, the precipitation temperature, the stirring intensity, the drug concentration and...
متن کاملLacidipine Loaded Solid Lipid Nanoparticles for Oral Delivery: Preparation, Characterization and In vivo Evaluation
The objective of this study was to develop and evaluate lacidipine (LD) loaded solid lipid nanoparticles (LD-SLNs) for improving the oral bioavailability. LD-SLNs were prepared in two steps. First step was hot homogenization and next by ultrasonication method, using triglycerides (tripalmitin and tristearin), monoglyceride and surfactants (Poloxamer 188 and egg lecithin E80). The prepared LDSLN...
متن کاملPreparation and Characterization of Manganese Ferrite Nanoparticles via Co-precipitation Method for Hyperthermia
In this work, Mn ferrite nanopowders were prepared by co-precipitation method and were characterized. Phase identification of the nanopowders was performed by X-ray diffraction method and the mean particle size of the nanopowders was calculated by Scherrer's formula, using necessary corrections. Magnetic parameters of the prepared nanopowders were measured by a vibrating sample magnetome...
متن کاملLiquid antisolvent precipitation process for solubility modulation of bicalutamide.
Liquid antisolvent process was explored as a solubility modulating tool. Bicalutamide, a poorly water soluble drug, was used as a candidate. Low aqueous solubility and poor dissolution of bicalutamide results into poor and variable bioavailability. Therefore, the objective of the present work was to modify the solubility of bicalutamide using the liquid antisolvent precipitation process. HPMC E...
متن کاملPreparation, Characterization and Antibacterial Activity of Manganese Oxide Nanoparticles
Manganese oxide nanoparticles (Mn3O4-NPs) were prepared using precipitation method. The prepared nanoparticles were characterized by a number of techniques, including X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Fourier transforms infra red (FT-IR) spectroscopy. The XRD pattern showed that the structure of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra10242a